Registration Dossier
Registration Dossier
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EC number: 204-707-7 | CAS number: 124-64-1
Endpoint summary
Administrative data
Description of key information
Key value for chemical safety assessment
Skin sensitisation
Link to relevant study records
- Endpoint:
- skin sensitisation
- Data waiving:
- study scientifically not necessary / other information available
- Justification for data waiving:
- other:
Reference
Endpoint conclusion
- Endpoint conclusion:
- adverse effect observed (sensitising)
- Additional information:
Skin Sens 1, H317: May cause an allergic skin reaction.
Migrated from Short description of key information:
read across from data/evidence based expert jugement:
THPC is considered a skin sensitiser based on two other existing data: a 20% THPC aqueous solution was found positive for skin sensitisation and a 75% THPS aqueous solution was found positive for skin sensitisation both by means of the GPMT (Magusson&Kligman)
Respiratory sensitisation
Endpoint conclusion
- Additional information:
- Migrated from Short description of key information:
The repiratory sensitisation potential has not been tested.
Technical THPC (80%) is an liquid solution. THPC is ionic compound which cannot be inhaled other than by means of an aerosol. Under intended conditions of use the formation of an aerosol is not a realistic exposure scenario for men.
Justification for classification or non-classification
Skin Sensitisation: data conclusive for classification (Skin Sens. Cat 1; H317).
Respiratory Sensistisation: test waived (no exposure); no classification required.
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