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Diss Factsheets

Ecotoxicological information

Short-term toxicity to fish

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Administrative data

Endpoint:
short-term toxicity to fish
Type of information:
experimental study
Adequacy of study:
other information
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: guideline study without detailed documentations

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1992
Report date:
1992

Materials and methods

Principles of method if other than guideline:
Method recommendation of the German Federal Environmental Agency "Letale Wirkung beim Zebrabaerbling Brachydanio rerio, Mai 1984". (lethal effect on Brachydanio rerio, May 1984)
GLP compliance:
no

Test material

Constituent 1
Chemical structure
Reference substance name:
2,2,4,6,6-pentamethylheptane-4-thiol
EC Number:
296-714-7
EC Name:
2,2,4,6,6-pentamethylheptane-4-thiol
Cas Number:
93002-38-1
Molecular formula:
C12H26S
IUPAC Name:
2,2,4,6,6-pentamethylheptane-4-thiol
Details on test material:
- Name of test material (as cited in study report): Tert. Dodecylmercaptan
- CAS No. as cited in study report: 25103-58-6 (tert. dodecanethiol), but the test material was material as defined in section 1 (CAS 93002-38-1). Therefore the new CAS number 93002-38-1 was assigned.

Sampling and analysis

Analytical monitoring:
not specified

Test organisms

Test organisms (species):
Danio rerio (previous name: Brachydanio rerio)

Study design

Test type:
static
Water media type:
freshwater
Limit test:
yes
Total exposure duration:
96 h

Test conditions

pH:
>= 6 - <= 8
Dissolved oxygen:
not less than 60 %

Results and discussion

Effect concentrations
Duration:
96 h
Dose descriptor:
LC0
Effect conc.:
10 000 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
mortality (fish)

Any other information on results incl. tables

Sublethal observations / clinical signs:

after 96 hour exposure a lethargic swimming behaviour was observed, but none of the teste animals died

Applicant's summary and conclusion

Executive summary:

The acute toxicity towards fish was tested according to the recommended method of the German Federal Environmental Agency "Letale Wirkung beim Zebrabaerbling Brachydanio rerio, Mai 1984" yielding no adverse effects up to the water solubilty limit of the test item (Bayer AG 1992).