Propanoic acid, 2-hydroxy-2-methyl-, 2-propen-1-yl ester

Melting point / freezing point

Administrative data

Endpoint:

melting point/freezing point

Type of information:

experimental study

Adequacy of study:

key study

Reliability:

1 (reliable without restriction)

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

2000

Report date:

2000

Materials and methods

Test guideline

Qualifier:

according to guideline

Guideline:

EU Method A.1 (Melting / Freezing Temperature)

Deviations:

no

GLP compliance:

yes (incl. QA statement)

Type of method:

thermal analysis

Test material

Test material information

Constituent 1

Reference substance name:

prop-2-en-1-yl 2-hydroxy-2-methylpropanoate

EC Number:

700-908-3

Cas Number:

19444-21-4

Molecular formula:

C7H12O3

IUPAC Name:

prop-2-en-1-yl 2-hydroxy-2-methylpropanoate

Results and discussion

Melting / freezing point

Melting / freezing pt.:

ca. -36.6 °C

Any other information on results incl. tables

EXPERIMENTAL DATA AND RESULTS

1st sample (FileF-1355):

 

7.684mg in a closed aluminium pan, crimped under N₂-atmosphere.

 

The substance was cooled down in the DSC from 25°C to -120°C with 100°C/min, then hold

isothermal during 10 minutes at -120°C.

In a subsequent heating curve with 10°C/min, the glass transition from the glassy state to the

liquid state can be measured at -105°C. At about -70°C the crystallization of the liquid and

subsequently the melting of the crystallized test item can be observed at -35.9°C. The melting

temperature is equal to the freezing temperature.

 

2ndsample (FileF-1357):

 

3.240 mg in a closed aluminium pan, crimped under N₂-atmosphere. 

The substance was cooled down in the DSC from 25°C to -120°C with 100°C/min, then hold isothermal during 10 minutes at -120°C.

In a subsequent heating curve with 100°C/min, the glass transition from the glassy state to the

liquid state can be measured at -105°C. At about -70°C the crystallization of the liquid and

subsequently the melting of the crystallized test item can be observed at -37.4"C. The melting

temperature is equal to the freezing temperature.

 

For example, the heating curve of the first is represented in figure1

Figure1: File F-1355

 

 

Results (from the heating curves after cooling phase)

 

File:	F_1355	F_1357
Heating Rate	10°C/min	10°C/min
Tg (glass transition-temperature)	-105.5°C	-105.2°C
Crystallization peak	-56.1°C	-56.1°C
Melting peak (= equal the freezing point)	-35.85°C	-37.39°C
Heat of fusion	76.68J/g	75.27J/g

 

Mean values

 

Tg (glass transition-temperature)	-105.5°C
Crystallization peak	-56.1°C
Melting peak (= equal the freezing point)	-36.6°C
Heat of fusion	76.0J/g

 

 

Applicant's summary and conclusion

Conclusions:

The melting/freezing temperature was determined by the DSC (Differential Scanning Calorimetry) method to be -36.6°C.