Registration Dossier
Registration Dossier
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EC number: - | CAS number: -
Bioaccumulation: aquatic / sediment
Administrative data
Link to relevant study record(s)
Description of key information
A bioconcentration study for B508 was performed in carp. Following a 60 day uptake period, steady state BCFs could be determined for a total of four different peaks (1, 2, 3 and 5), observed in the LC-MS chromatogram. The highest BCF values were determine for peak 5 (i. e. hydrogenated rosins): 584 at exposure concentration 1.5 µg/L and 545 at exposure concentration 15 µg/L.
The BCF study was carried out according to OECD (305) and GLP guidelines. However, a depuration phase was required since the estimated BCFs were higher than 10 for most of the peaks. As the depuration phase was not performed, the study is classified as reliable with restrictions.
Key value for chemical safety assessment
- BCF (aquatic species):
- 584 dimensionless
Additional information
The BCF value of 584 at exposure concentration of 1.5 µg/L of peak 5 (i.e. hydrogenated rosins) was taken as a worst case value.
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