Registration Dossier

Manufacture, use & exposure

Manufacture

Manufacture

Manufacture name:
synthesis
Contributing activity / technique for the environmentopen allclose all
Environmental release category (ERC):
ERC1: Manufacture of the substance
Name of activity / technique:
Closed batch process: synthesis of 2-amino-6-{[(3S)-1-(3-methylbutanoyl)piperidin-3-yl]methoxy}benzonitrile
Contributing activity / technique for workersopen allclose all
Process category (PROC):
PROC 3: Manufacture or formulation in the chemical industry in closed batch processes with occasional controlled exposure or processes with equivalent containment conditions
Process category (PROC):
PROC 8b: Transfer of substance or mixture (charging and discharging) at dedicated facilities
Name of activity / technique:
Closed batch process: synthesis of 2-amino-6-{[(3S)-1-(3-methylbutanoyl)piperidin-3-yl]methoxy}benzonitrile
Process category (PROC):
PROC 3: Manufacture or formulation in the chemical industry in closed batch processes with occasional controlled exposure or processes with equivalent containment conditions
PROC 8b: Transfer of substance or mixture (charging and discharging) at dedicated facilities

Contributing scenario for the environment (related to workers activities)

Conditions of use for the environment

Product (article) characteristic

Amounts used, frequency and duration of use (or from service life)

Technical and organisational conditions and measures

Other technical and organisational conditions
Effectiveness
Route affected:
air

Conditions and measures related to Biological Sewage Treatment Plant

Biological Sewage Treatment Plant (STP):
no
Application of site specific biological STP sludge on agricultural soil:
no

Conditions and measures related to external treatment of waste (including article waste)

Other conditions of use

Other conditions affecting environmental exposure

Exposure of the environment

PECopen allclose all
Exposed compartment:
freshwater
Exposed compartment:
sediment (freshwater)
Exposed compartment:
marine water
Exposed compartment:
sediment (marine water)
Exposed compartment:
predators' prey (freshwater)
Exposed compartment:
predators' prey (marine water)
Exposed compartment:
top predators' prey (marine water)
Exposed compartment:
sewage treatment plant
Exposed compartment:
agricultural soil
Exposed compartment:
predators' prey (terrestrial)
Exposed compartment:
air

Contributing scenario for the workers

Conditions of use for workers

Product (article) characteristics

Amounts used (or contained in articles), frequency and duration of use/exposure

Technical and organisational conditions and measures

TechCondRepopen allclose all
Effectiveness
Route affected:
inhalation
Effectiveness
Route affected:
dermal
Effectiveness
Route affected:
eye

Conditions and measures related to personal protection, hygiene and health evaluation

PPERepopen allclose all
Effectiveness
Route affected:
inhalation
Effectiveness
Route affected:
dermal
Effectiveness
Route affected:
eye

Other conditions affecting workers exposure

Place of use:
indoor