Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Physical & Chemical properties

Partition coefficient

Currently viewing:

Administrative data

partition coefficient
Type of information:
migrated information: read-across from supporting substance (structural analogue or surrogate)
Adequacy of study:
other information
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: GLP status not known, information from published handbook, acceptable with restrictions

Data source

Reference Type:
review article or handbook
CRC Handbook of Chemistry and Physics, 89th Edition.
Lide, D. (Ed)
Bibliographic source:
CRC Press Inc. Boca Raton. USA.

Materials and methods

Principles of method if other than guideline:
The use of secondary sources of data is acceptable when they are based on a critical evaluation of peer-reviewed data and a consequent selection of a reliable and representative value for the property under investigation. The introduction to the CRC Handbook of Chemistry and Physics states that data for physical constants have been taken from many sources, including both compilations and the primary literature. Where conflicts were found, the value deemed most reliable was chosen. Therefore, although the method used is not known, the values presented here are acceptable as they are from a reliable secondary source of phys chem. data.
GLP compliance:
not specified
Type of method:
other: No data reported
Partition coefficient type:

Test material

Constituent 1
Chemical structure
Reference substance name:
Acetic acid
EC Number:
EC Name:
Acetic acid
Cas Number:
Molecular formula:
acetic acid
Details on test material:
No data reported

Study design

Analytical method:
not specified

Results and discussion

Partition coefficient
log Pow
Partition coefficient:
25 °C
Details on results:
No data reported. pH and temperature assumed.

Applicant's summary and conclusion

The log Pow of acetic acid is -0.17
Executive summary:

No information on the primary source of this data or the methods used is available. However, this information is taken from a reliable peer reviewed handbook and so can be considered reliable and suitable for use as the key study for this endpoint.