Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 265-450-4 | CAS number: 65113-95-3
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
The acute toxicity of MTCP Crude is estimated to give a 96-Hour LC50 value of 2.3 mg/l based on read-across from an appropriate structural analogue.
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 2.3 mg/L
Additional information
An appropriate structural analogue (3-methyl-5-(2,2,3-trimethylcyclopent-3-en-1-yl)pent-4-en-2-ol), tradename Ebanol, has been tested for short-term toxicity to fish.
The 96-Hour LC50 based on nominal test concentrations was 2.3 mg/l with 95% confidence limits of 1.7 - 3.0 mg/l. The No Observed Effect Concentration was 0.96 mg/l.
Analysis of the saturated solution, used to prepare the test concentrations, at 0 and 72 hours showed measured concentrations of 25.7 and 32.5 mg/l respectively (86% and 108% of nominal respectively). The results from the freshly prepared media at 0 and 72 hours showed measured concentrations to range from 80% to 102% of nominal. Results from the old media at 24 and 96 hours showed a decline in measured concentrations over the 24-Hour dosing periods with results ranging from 48% to 87% of nominal.
The test item is known to be stable in the test media over a 24-Hour period and has also been shown to be stable over a 72-Hour period for the Algal Inhibition study (Harlan Laboratories Ltd Project Number: 0766/0176). As both tests conducted were similarly covered, losses due to volatilisation were not expected. It was therefore considered that the decline in measured concentrations over the 24-Hour dosing periods was possibly due to adsorption to the test organisms and/or organic waste. It was therefore considered justifiable to base the results on nominal test concentrations only.
The study met the acceptability criteria prescribed by the study plan and was considered valid.
The aquatic toxicity of the analogue test substance (Ebanol) is anticipated to be similar to that of MTCP Crude (see read-across justification document in section 13 for details). Therefore, the 96 hour LC50 of MTCP Crude based on nominal test concentrations is also considered to be 2.3 mg/L.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
