Registration Dossier
Registration Dossier
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EC number: 700-202-5 | CAS number: 765-63-9
Additional ecotoxological information
Administrative data
- Endpoint:
- additional ecotoxicological information
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Study period:
- 9 – 10 March 2010
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Non GLP study and no standard method used (feasibility study)
Cross-reference
- Reason / purpose for cross-reference:
- reference to other study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 010
- Report date:
- 2010
Materials and methods
Test guideline
- Qualifier:
- no guideline required
- Principles of method if other than guideline:
- Feasibility trial to investigate suitable method for formulation of test media for use in aquatic toxicity testing.
- GLP compliance:
- no
Test material
- Reference substance name:
- 2,2,3,3-tetrafluorooxetane
- EC Number:
- 700-202-5
- Cas Number:
- 765-63-9
- Molecular formula:
- C3H2F4O
- IUPAC Name:
- 2,2,3,3-tetrafluorooxetane
- Details on test material:
- - Name of test material (as cited in study report): TFO
- Substance type: organic
- Physical state: liquid
- Analytical purity: 99%
- Lot/batch No.: TFOS285001
- Expiration date of the lot/batch: 30 April 2010
- Storage condition of test material: not reported
Constituent 1
Results and discussion
Any other information on results incl. tables
Under the test conditions employed, it was not possible to achieve the nominal concentrations and this is presumed to be due to the volatility of the test material. These results suggest that the type of medium used did not affect the test concentration achieved and the use of solvent stock solutions was not beneficial.
Applicant's summary and conclusion
- Conclusions:
- It is proposed that range finding tests are performed under sealed conditions, at nominal concentrations of 0.1, 1, 10 and 100 mg TFO/L, with test media prepared via direct addition of the test material to the dilution media. The time taken for media preparation will be kept to a minimum in an attempt to minimise any losses by volatility.
- Executive summary:
Under the test conditions employed, it was not possible to achieve the nominal concentrations and this is presumed to be due to the volatility of the test material. These results suggest that the type of medium used did not affect the test concentration achieved and the use of solvent stock solutions was not beneficial.
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