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EC number: 700-823-1
CAS number: 55514-22-2
Lack of absorption shown in toxicokinetics (satellite groups in OECD 422
reliability 1 study) and dermal penetration studies (OECD 428 studies
performed on Human untreated or altered skin) has been confirmed in all
toxicology studies results:
- acute oral toxicity (LD50 > 2000 mg/kg)
- acute dermal toxiciy (LD50 > 2000 mg/kg
- irritation (non irritant in OECD 404 skin irritation study, HET-CAM
assay, rabbit cornea fiboblast neutral red release)
- sensitisation (non sensitiser in a LLNA test)
- OECD 422 study concluding with a NOEL > 1000 mg/kg for repeated
toxicity endpoints and reproductive endpoint
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