Registration Dossier

Administrative data

Endpoint:
acute toxicity: oral
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: Guideline study, GLP compliance

Data source

Reference
Reference Type:
other: study summaries submitted to ECHA more than 12 years ago
Title:
Unnamed
Year:
2011

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
other: OECD 401 (1987)
GLP compliance:
yes
Test type:
standard acute method
Limit test:
yes

Test material

Reference
Name:
Unnamed
Type:
Constituent

Test animals

Species:
other: rat, TIf:RAlf(SPF)

Administration / exposure

Vehicle:
other: Distilled water containing 0.5% carboxymethylcellulose and 0.1 %polysorbate 80.

Results and discussion

Effect levels
Sex:
male/female
Dose descriptor:
LD50
Effect level:
> 2 000 mg/kg bw
Mortality:
Male: 2000 mg/kg bw; Numberof animals: 5; Numberof deaths: 0
Female: 2000 mg/kg bw; Numberof animals: 5; Numberof deaths: 0
Clinical signs:
Signsof toxicity related to dose levels:
Unspecific symptoms of intoxication: piloerection, hunched
posture. exophthalmus and dyspnoea.
Gross pathology:
Effectson organs: no effects

Applicant's summary and conclusion

Interpretation of results:
not classified
Remarks:
Migrated information Criteria used for interpretation of results: EU