Registration Dossier

Administrative data

Description of key information

Read-across from acute oral, dermal and inhalation studies with cyanuric acid. Experimental data showed no evidence of acute toxicity to cyanuric acid. 

Key value for chemical safety assessment

Acute toxicity: via oral route

Endpoint conclusion
Dose descriptor:
LD50
7 554.42 mg/kg bw

Acute toxicity: via inhalation route

Endpoint conclusion
Dose descriptor:
LC50
7 930 mg/m³

Acute toxicity: via dermal route

Endpoint conclusion
Dose descriptor:
LD50
7 554.42 mg/kg bw

Additional information

Read-across:
1. Based on the experimental results obtained with the analogue cyanuric acid (LD50 > 5000 mg/kg bw) the read-across approach is applied and the LC50 for substance trisodium cyanurate is calculated to be higher than 7554.42 mg/kg bw (oral acute toxicity).
2. Based on the experimental results obtained with the analogue cyanuric acid (LC50 > 5.25 mg/L) the read-across approach is applied and the LC50 for substance trisodium cyanurate is calculated to be higher than 7.93 mg/L (inhalation acute toxicity).
3. Based on the experimental results obtained with the analogue cyanuric acid (LD50 > 5000 mg/kg bw) the read-across approach is applied and the LC50 for substance trisodium cyanurate is calculated to be higher than 7554.42 mg/kg bw (dermal acute toxicity).

Justification for classification or non-classification

The LD50 values exceeded the limit of classification in the oral, dermal and inhalation studies and therefore CYA need not be classified.