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Diss Factsheets

Physical & Chemical properties

Melting point / freezing point

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Administrative data

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Endpoint:
melting point/freezing point
Type of information:
experimental study
Adequacy of study:
key study
Study period:
February 26, 2002
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
OECD Guideline 102 (Melting point / Melting Range)
Version / remarks:
Cited as Directive 92/69/EEC, A.1
GLP compliance:
yes (incl. QA statement)
Type of method:
method to determine freezing temperature
Key result
Melting / freezing pt.:
> 7.5 - <= 7.7 °C
Atm. press.:
>= 96 000 - <= 96 800 Pa
Decomposition:
no
Sublimation:
no
Two independent determinations were carried out:
Assay no. 1:
Atmospheric pressure: 96.8 kPa
Test room hygrometry: 34.5%
Freezing point: 7.7 +/- 0.1 deg.C
Assay no. 2:
Atmospheric pressure: 96.0 kPa
Test room hygrometry: 41 %
Freezing point: 7.5 +/- 0.1 deg.C
Conclusions:
Under the study conditions, the freezing point of the test substance was established to be 7.6 +/- 0.1°C at 96,400 Pa.
Executive summary:

A study was conducted to determine the freezing point of the test substance according to the OECD Guideline 102 and EU Method A.1, in compliance with GLP. Under the study conditions, the freezing point of the test substance was established to be 7.6 +/- 0.1°C at 96,400 Pa (Mourgues, 2002).

Endpoint:
melting point/freezing point
Type of information:
experimental study
Adequacy of study:
key study
Study period:
From October 15, 2004 to December 22, 2004
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
EU Method A.1 (Melting / Freezing Temperature)
GLP compliance:
yes (incl. QA statement)
Type of method:
method to determine freezing temperature
Remarks:
A1 92/69/EC
Key result
Melting / freezing pt.:
10.9 °C
Decomposition:
no
Conclusions:
Under the study conditions, the freezing point of the test substance was estimated at 10.9°C.
Executive summary:

The study was conducted to determine the freezing point of the test substance according to the EU Method A.1, in compliance with GLP. Under the study conditions, the freezing point of the test substance was estimated at 10.9°C (White, 2004).

Description of key information

Determination of the melting point according to OECD Guideline 102 and EU Method A.1 (Mourgues, 2002; White, 2004).

Key value for chemical safety assessment

Melting / freezing point at 101 325 Pa:
7.6 °C

Additional information

- 7.6 +/- 0.1°C at 96,400 Pa (Mourgues, 2002)

- 10.9°C (White, 2004)