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EC number: 208-011-4 | CAS number: 505-52-2
Read across from dodecanedioic acid (CAS 693-23-2) - Subchronic NOAEL (rat): 1800 mg/kg bw/day (OECD 408, GLP)
A repeated dose oral 13 week study was conducted in rats with the test substance dodecanedioic acid. No changes of toxicological importance were seen at any of the dose levels tested and, therefore, the NOAEL was 1800 mg/kg bw/day.
There is no repeated dose toxicity data available for tridecanedioic acid (CAS No. 505-52-2) A read-across approach was conducted with data from a 90 day oral repeated dose toxicity study from dodecanedioic acid (CAS 693-23-2).
The complete read across justification is attached as document.
Based on available information in the dossier, the substance tridecanedioic acid (CAS No. 505-52-2) does not need to be classified as specific target organ toxicity (repeated) when considering the criteria outlined in Annex I of 1272/2008/EC based on the results of the read-across study from dodecanedioic acid (CAS 693-23-2).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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