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Physical & Chemical properties

Partition coefficient

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Description of key information

Due to rapid hydrolysis of SIKA Hardener LI (see: Section 5.1.2 on hydrolysis study) upon contact with water, measurement of the partition coefficient of SIKA Hardener LI was technically not feasible. Instead the log Pow of the hydrolysis product were determined. The log Pow of the hydrolysis product was determined to be log Pow 7.41.

Key value for chemical safety assessment

Log Kow (Log Pow):
7.41
at the temperature of:
20 °C

Additional information

Waiving statement

In accordance with column 2 adaptation statement of Annex VII Regulation (EC) No 1907/2006 (REACH), the determination of the partition coefficient (as required in section 7.8 of Annex VII) the study does not need to be conducted as the substance decompose (fast hydrolysis) during the performance of the test. Thus the experimental determination was replaced by an appropriate calculation method. Please refer to IUCLID section 5.1 for more details about hydrolysis.

 

Model prediction

Using KOWWIN v.168 the log Kow of SIKA Hardener LI was calculated to be 16.97 at 25 °C (EPI Suite, 2014). The substance is not within the applicability domain of the model. Therefore the estimation may be less accurate. The QMRF and QPRF documentation are attached to the respective study record.

 

Supporting studies

The partition coefficient (n-octanol/water) of the first hydrolysis product (Aldehyde L) of the test item was assessed in accordance with OECD guideline no. 117, EU method A.8 and OPPTS 830.7570 guideline. In the course of this study the partition coefficient (Pow) of Aldehyde L was determined using high performance liquid chromatography. Retention times of components of Aldehyde L are higher than the last eluting standard (DDT); therefore an accurate value of log Pow could not be given. The extrapolated log Pow value calculated for Aldehyde L (peak 1, retention time: 12.56 minutes) and Aldehyde L (peak 2, retention time: 13.53 minutes) are 7.20 and 7.41, respectively.

 

Furthermore s study was conducted according to Regulation (EC) 440/2008 Part A A.8 to determine the logPow of the second hydrolysis product of the test item. Using the shake flask method the log Pow was determined to be 0.99 at 23 °C.

 

Conclusion

In conclusion the logPow of the first hydrolysis product was regarded as worst case. Consequently a logPow of 7.41 was chosen as key value for chemical safety assessment.