Registration Dossier
Registration Dossier
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EC number: 215-608-3 | CAS number: 1333-83-1
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
A number of non-guideline studies performed with sodium fluoride are available. EC50 values for marine invertebrates range from 10.5-39 mg/L. EC50 values for daphnids range from 97-352 mg/L; benthic insect larvae were found to be more sensitive, with EC50 values of 26-48 mg/L (test with soft water).
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 26 mg/L
Marine water invertebrates
Marine water invertebrates
- Effect concentration:
- 10.5 mg/L
Additional information
Camargo & Tarazona (1991) report that benthic larvae are sensitive to the concentration of fluoride, with EC50 values ranging from 26 -48 mg/L (actual concentration); however the study was performed in soft water. The EU RAR reviews and summarises the available data on short-term toxicity to aquatic invertebrates. The reported EC50 values for Daphnia sp. range from 97-352 mg/L and are based on nominal concentrations; EC50 values of 10.5 -39 mg/L are reported for marine invertebrates. The ICD summarises the available data on the short-term toxicity of sodium fluoride to aquatic invertebrates and reports EC50 values of 109 -340 mg/L; EC50 values of 30 -500 mg/L are reported for marine invertebrates.
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