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Physical & Chemical properties

Boiling point

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Reference
Endpoint:
boiling point
Type of information:
experimental study
Adequacy of study:
key study
Study period:
From July 30 to August 07, 2014
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Remarks:
The study was conducted according to an internationally recognised method, and under GLP. The substance is adequately characterised with its isomers composition. Therefore full validation applies.
Qualifier:
according to guideline
Guideline:
OECD Guideline 103 (Boiling point/boiling range)
Deviations:
no
Qualifier:
according to guideline
Guideline:
EU Method A.2 (Boiling Temperature)
Deviations:
no
Principles of method if other than guideline:
Not applicable
GLP compliance:
yes (incl. QA statement)
Remarks:
inspected on November 29 and 30, 2010 / signed on April 11, 2011
Type of method:
method according to Siwoloboff
Key result
Boiling pt.:
327 °C
Atm. press.:
1 013 hPa
Decomposition:
no

Table 4.3/1: Observations

 

Determination

Boiling Point

Atmospheric Pressure

Second determination

294.4 °C (567.6 K)

99904 Pa

Third determination

326.7 °C (599.9 K)

99683 Pa

Fourth determination

325.2 °C (598.4 K)

99673 Pa

 

The duplicate determination (experiments 2 and 3) showed unusual variation. Therefore, it was decided to perform a fourth experiment. As the fourth determination confirmed the result of the third determination, experiments 3 and 4 were used for evaluation. After cooling down, the test item was unchanged.

 

Table 4.3/2: Corrected values following Sidney-Young

 

Determination

Boiling Point

Pressure in Pa

Corrected Boiling Point

Third determination

326.7 °C (599.9 K)

99683 Pa

327.6 °C (600.7 K)

Fourth determination

325.2 °C (598.4 K)

99673 Pa

326.1 °C (599.2 K)

Mean

326.9 °C (600.0 K)

 

Mean ± standard deviation (after correction following Sydney Young) = 326.9 ± 1.1 °C (600.0 ± 1.1 K).

 

Executive summary:

The boiling point of the test substance was determined under GLP according to OECD 103/EU A2 guideline, by Siwoloboff (capillary) method.

The determination was performed in triplicate and the mean final temperature was retained (2 consistent results), and corrected to normal atmospheric pressure. No change in appearance was observed.

 

The normal boiling point (corrected to standard atmP) of the test substance was determined as 327°C.

Description of key information

Measured (initial) boiling point = 326°C under 99.7 kPa; Corrected value = 327°C to normal atmP

Key value for chemical safety assessment

Boiling point at 101 325 Pa:
327 °C

Additional information

A fully reliable experimental study, conducted according to a recognized OECD/EC method and under GLP, is available. Therefore it is considered as a key study, and the result is retained as key data.