Registration Dossier

Diss Factsheets

Administrative data

Endpoint:
sub-chronic toxicity: dermal
Type of information:
read-across based on grouping of substances (category approach)
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Justification for type of information:
See category justification

Data source

Materials and methods

Test material

1
Chemical structure
Reference substance name:
1-(1-methyl-2-propoxyethoxy)propan-2-ol
EC Number:
249-949-4
EC Name:
1-(1-methyl-2-propoxyethoxy)propan-2-ol
Cas Number:
29911-27-1
Molecular formula:
C9H20O3
IUPAC Name:
1-(1-methyl-2-propoxyethoxy)propan-2-ol
Test material form:
liquid

Test animals

Species:
rat

Results and discussion

Effect levels

Dose descriptor:
NOAEL
Based on:
test mat.
Sex:
male/female
Remarks on result:
not determinable due to absence of adverse toxic effects
Remarks:
up to the limit dose of 1000mg/kgbw/day. Conclusion based on an extrapolation of data on the substance itself and other members of the category.

Target system / organ toxicity

Critical effects observed:
no

Applicant's summary and conclusion