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Toxicity to microorganisms

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Description of key information

The "Minimum Inhibitory Concentration (MIC100)" value of calcium iodate based on effect of growth inhibition of Clostridium sp. in a 24 hr study was estimated to be 509.603 mg/L.

Key value for chemical safety assessment

Additional information

Based on the various studies available with Klimish rating 2 for the read across substances for CAS NO 7789-80-2 and based on the category approach of organic functional group along with similar mechanistic approach and having structural similarities defined by QSAR toolbox. The results is summarized as follows

 

Sr.No

Endpoint

Effect values

Basis for effects

Duration

Species

Remarks

1

MIC

509.603 mg/l

growth inhibition

24 hrs

Clostridium sp.

Predicted data for target chemical

2

MIC

518.4457 mg/l

growth inhibition

24 hrs

Escherichia coli (JKE029)

Predicted data for target chemical

3

MIC

358.3 mg/l

growth inhibition

24 hrs

Staphylococcus auerus (JKB068

Data from publication for CAS no 7681-11-0

4

MIC

219.4 mg/l

growth inhibition

24 hrs

Escherichia coli (JKE029)

Data from publication for CAS no 7681-11-0

5

MIC

147.6 mg/l

growth inhibition

24 hrs

Bacillus subitilis (JKS007)

Data from publication for CAS no 7681-11-0

6

MIC

231.5 mg/l

growth inhibition

24 hrs

Clostridium sp. 1

Data from publication for CAS no 7681-11-0

7

MIC

200.9 mg/l

growth inhibition

24 hrs

Clostridium sp. 2

Data from publication for CAS no 7681-11-0

 

By applying weight of evidence approach to the studies summarized in the above table it can be observed that MIC (Minimum Inhibitory Concentration) value is expected to be in range of147.6 to 518.4457 mg/l