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Ecotoxicological information

Toxicity to aquatic algae and cyanobacteria

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Description of key information

In a good quality and reliable OECD guideline study conducted on C12-14 ADMAES in Pseudokirchnerella subcapitata, the ErC10 (0 -72 hours) and ErC50 were 0.01 and 0.14 mg a.i./L, respectively. The NOEC for effect on algal growth and growth rate was determined to be 0.008 mg a.i./L.

Key value for chemical safety assessment

EC50/LC50 for freshwater algae:
0.14 mg/L
EC10, LC10 or NOEC for freshwater algae:
0.01 mg/L

Additional information

An OECD guideline study was conducted to determine the toxicity of C12-14 ADMAES to the algae Pseudokirchnerella subcapitata. Algae were exposed to the test substance at nominal concentrations of 0.005, 0.013, 0.031, 0.08 and 0.19 mg a.i./L. Algal cell concentrations were determined spectrophotometrically. All the validity criteria were fulfilled. Analytical assessment was performed for the test substance in aqueous samples, at the beginning, middle and at the end of the test. Procedures and instrumentation were based on High Performance Liquid Chromatography combined with mass spectrometry (LC-MS/MS). The test substance concentration decreased to below 80% of the nominal and initial concentrations during the test. This is because surfactant based substances are known to bind to algae cells actually stimulating complete exposure. This is however not measurable analytically as removing the test substance entirely from the algae cells, making it available for analysis is not always achievable. This difficulty is acknowledged in the OECD test guideline and a use of the measured initial concentration is therefore considered acceptable for this type of test substance. Under the study conditions, the ErC10 (0-72 h) and ErC50 were 0.01 and 0.14 mg a.i./L, respectively. The NOEC for effects on algal growth and growth rate was determined to be 0.008 mg a.i./L (Kean M et al., 2012).