3,5-dimethylpyrazole

Density

Link to relevant study record(s)

Reference

Endpoint:

density

Remarks:

density

Type of information:

experimental study

Adequacy of study:

key study

Study period:

04 May to 17 August 2012

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

other: see 'Remark'

Remarks:

Study conducted in compliance with agreed protocols, with no or minor deviations from standard test guidelines and/or minor methodological deficiencies, which do not affect the quality of the relevant results. The study report was conclusive, with experiments conducted according to appropriate and valid guidelines and conducted under GLP conditions.

Qualifier:

according to guideline

Guideline:

EU Method A.3 (Relative Density)

Deviations:

no

Qualifier:

according to guideline

Guideline:

OECD Guideline 109 (Density of Liquids and Solids)

Deviations:

no

Qualifier:

according to guideline

Guideline:

EPA OPPTS 830.7300 (Density / Relative Density / Bulk Density)

Deviations:

no

GLP compliance:

yes

Type of method:

pycnometer method

Key result

Type:

density

Density:

1.14 g/cm³

Temp.:

20 °C

Remarks on result:

other: Temperature ± 0.5ºC

Results

The individual measurements were obtained with an accuracy of < 0.02 g/cm³. According to the guideline, the density of the test substance is given as the mean value.

 

Table 2. Results

	Test 1	Test 2	Test 3	Average
Density (g/cm³)	1.142	1.138	1.14	1.14

Conclusions:

Under the conditions of the test, the density of the test material was determined to be 1.14 g/cm³ at 20 ± 0.5ºC.

Executive summary:

The density of the test material was determined using the pycnometer method; the study was performed in accordance with GLP and to the standardised guidelines OECD 109, EU method A.3 and EPA OPPTS 830.7300.

The density was determined in three independent tests and the average selected as the representative value. Under the conditions of the test, the density of the test material was determined to be 1.14 g/cm³ at 20 ± 0.5ºC.

Description of key information

The density of 3,5-Dimethylpyrazole was determined to be 1.14 g/cm³ in a key study (Baltussen, 2012) performed according to OECD 109, EU method A.3 and EPA OPPTS 830.7300; all other sources have been provided as supporting data.

Key value for chemical safety assessment

Relative density at 20C:

1.14

Additional information

The density of the test material has been addressed by providing one key study and two supporting studies.

Baltussen (2012) has been provided as the key study, where the density was determined to be 1.14 g/cm³ using the using the pycnometer method. The study was performed in line with GLP and standardised guidelines and had thus been assigned a reliability score of 1 using the principles for assessing data quality as set out in Klimisch (1997).

Lide (2010) a peer reviewed handbook and Guidechem (2012) an internet source have both been provided as supporting data, who report the density to be 0.8839 and 1.026 g/cm³, respectively. Lide (2010) has been assigned a reliability score of 2 where as Guidechem (2012) has been assigned a reliability score of 4, according to the principles of Klimisch (1997).