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Physical & Chemical properties

Partition coefficient

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Description of key information

Estimated value based on solubility ratio:

log Pow= >5.4 <6.4 at 23°C

Measured value by HPLC:

log Pow= >6.5 at 23°C and at pH 6.4

Key value for chemical safety assessment

Additional information

The partition coefficient was measured by HPLC and estimated from the single solubilities in n-octanol and in water.

Further the partition coefficient have been additionally calculated using different programs as recommended in Guideline.

- The calculation by KOWWIN module is given a log Pow value of 5.6.

- The calculated values by ACD/Labs are given as follows:

logD= 6.8 at pH 4-7 at 25°C

logD= 6.5 at pH 9 at 25°C