Registration Dossier
Registration Dossier
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EC number: 939-266-6 | CAS number: 1179883-13-6
Sediment toxicity
Administrative data
Link to relevant study record(s)
Description of key information
EC50 (10 d) = 650.45 mg a.i./kg dw for Corophium sp. (OSPARCOM 1995) (read-across)
Key value for chemical safety assessment
- EC50 or LC50 for marine water sediment:
- 650.45 mg/kg sediment dw
- EC10, LC10 or NOEC for marine water sediment:
- 71.36 mg/kg sediment dw
Additional information
There are no data available on sediment toxicity of D-Glucose, reaction products with alcohols C16-18 (even numbered) (excess). However, there are reliable data for category member substances which are considered suitable for read-across based on a category approach. This read-across is in accordance with Regulation (EC) No. 1907/2006 Annex XI, 1.5 and justified in detail in the overall summary (IUCLID Chapter 6.1) and within the category justification attached in IUCLID Section 13. In this case of read-across, the best suited (highest degree of structural similarity, nearest physico-chemical properties) read-across substance was used for the assessment. Nevertheless, as it can be seen in the data matrix of the category justification in IUCLID Section 13 and the overall summary (IUCLID Chapter 6.1), all reliable data in the category support the hazard assessment of each category member by showing a consistent pattern of results.
The toxicity of D-Glucopyranose, oligomeric, C10-16-alkyl glycosides towards sediment organisms was investigated in a short-term study with the endobenthic marine amphipod Corophium volutator (ERT Ltd, 2001). The test was performed according to the OSPARCOM guideline (1995): Sediment bioassay using an amphipod Corophium sp. At test termination after 10 days, a LC50 of 650.45 mg a.i./kg sediment dw and a NOEC of 71.36 mg/kg sediment dw resulted based on mortality.
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