Registration Dossier
Registration Dossier
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EC number: 939-266-6 | CAS number: 1179883-13-6
Adsorption / desorption
Administrative data
Link to relevant study record(s)
Description of key information
Moderate potential for adsorption to soil and sediment particles (estimated log Koc 0.6677 to 4.805, measured log Koc 1.7)
Key value for chemical safety assessment
Additional information
No studies on adsorption/desorption are available for D-Glucose, reaction products with alcohols C16-18 (even numbered) (excess). However, there are reliable data for category member substances which are considered suitable for read-across based on a category approach. This read-across is in accordance with Regulation (EC) No. 1907/2006 Annex XI, 1.5 and justified in detail in the overall summary (IUCLID Chapter 5) and within the category justification attached in IUCLID Section 13. In this case of read-across, the best suited (highest degree of structural similarity, nearest physico-chemical properties) read-across substance was used for the assessment. Nevertheless, as it can be seen in the data matrix of the category justification in IUCLID Section 13 and the overall summary (IUCLID Chapter 5), all reliable data in the category support the hazard assessment of each category member by showing a consistent pattern of results.
The adsorption coefficient (log Koc) of the category member D-Glucopyranose, oligomeric, C10-16-alkyl glycosides was estimated according to the OECD guideline 121 using High Performance Liquid Chromatography (HPLC). Seven reference substances with known adsorption coefficients were used for determination of the log Koc. The capacity factor k’ was calculated for each reference substance and related to the corresponding log Koc values to draw a calibration curve. The test substance elutes in a distribution of 5 chromatographic peaks. Considering the corresponding peak areas, the weighted average adsorption coefficient log Koc of D-Glucopyranose, oligomeric, C10-16-alkyl glycosides is 1.7 at 25 °C (Henkel, 2010). This data is considered as read-across within a category approach.
Using KOCWIN v2.00, log Koc values of 0.6677 to 3.1513 (estimate from log Kow) and 1.4173 to 4.805 (estimate from MCI method) were calculated using smiles notations, indicating a moderate adsorption potential of the substance to soil and sediment particles.
Besides, further testing is not justified as the substance is readily biodegraded.
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