Registration Dossier

Guidance on Safe Use

Guidance on Safe Use

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Administrative data

First-aid measures

General advice: In the case of accident or if you feel unwell, seek medical advice immediately.
When symptoms persist or in all cases of doubt seek medical advice.
Protection of first-aiders: No special precautions are necessary for first aid responders.
If inhaled : If inhaled, remove to fresh air.
Get medical attention if symptoms occur.
In case of skin contact: Thaw frosted parts with lukewarm water. Do not rub affected area.
Get medical attention immediately.
In case of eye contact: Get medical attention immediately.
If swallowed: Ingestion is not considered a potential route of exposure.

Most important symptoms and effects, both acute and delayed
Symptoms: Inhalation of high concentration may cause
Cardiac sensitisation
Anaesthetic effects
Lack of coordination
May cause cardiac arrhythmia.

Risks: Contact with liquid or refrigerated gas can cause cold burns and frostbite.

Indication of any immediate medical attention and special treatment needed
Treatment: Because of possible disturbances of cardiac rhythm, cate-cholamine drugs, such as epinephrine, that may be used in situations of emergency life support should be used with special caution.

Fire-fighting measures

Extinguishing media
Suitable extinguishing media: Not applicable
Will not burn
Unsuitable extinguishing media: Not applicable
Will not burn
Special hazards arising from the substance or mixture
Specific hazards during fire-fighting: Exposure to combustion products may be a hazard to health.
If the temperature rises there is danger of the vessels bursting due to the high vapor pressure.

Hazardous combustion products: No hazardous combustion products are known

Advice for firefighters
Special protective equipment for firefighters: Wear self-contained breathing apparatus for firefighting if necessary. Use personal protective equipment.

Specific extinguishing methods: Use extinguishing measures that are appropriate to local cir-cumstances and the surrounding environment.
Fight fire remotely due to the risk of explosion.
Use water spray to cool unopened containers.
Remove undamaged containers from fire area if it is safe to do so.
Evacuate area.

Accidental release measures

Personal precautions, protective equipment and emergency procedures
Personal precautions: Evacuate personnel to safe areas.
Avoid skin contact with leaking liquid (danger of frostbite).
Ventilate the area.
Follow safe handling advice and personal protective equipment recommendations.
Environmental precautions
Environmental precautions: Prevent further leakage or spillage if safe to do so.
Retain and dispose of contaminated wash water.
Methods and material for containment and cleaning up
Methods for cleaning up : Ventilate the area.
Local or national regulations may apply to releases and disposal of this material, as well as those materials and items employed in the cleanup of releases.

Handling and storage

Precautions for safe handling
Technical measures: Use equipment rated for cylinder pressure. Use a backflow preventative device in piping. Close valve after each use and when empty.
Local/Total ventilation : Use only with adequate ventilation.

Advice on safe handling : Handle in accordance with good industrial hygiene and safety practice, based on the results of the workplace exposure assessment
Wear cold insulating gloves/ face shield/ eye protection.
Prevent backflow into the gas tank.
Open the valves slowly to prevent pressure surges.
Close valve after each use and when empty. Do NOT change or force fit connections.
Prevent the intrusion of water into the gas tank.
Keep away from heat and sources of ignition.
Take precautionary measures against static discharges.
Take care to prevent spills, waste and minimize release to the environment.
Avoid breathing gas.
Valve protection caps and valve outlet threaded plugs must remain in place unless container is secured with valve outlet piped to use point.
Use a check valve or trap in the discharge line to prevent haz-ardous back flow into the cylinder.
Use a pressure reducing regulator when connecting cylinder to lower pressure (<3000 psig) piping or systems.
Never attempt to lift cylinder by its cap.
Do not drag, slide or roll cylinders.
Use a suitable hand truck for cylinder movement.
Hygiene measures: If exposure to chemical is likely during typical use, provide eye flushing systems and safety showers close to the working place. When using do not eat, drink or smoke. Wash contaminated clothing before re-use.
Conditions for safe storage, including any incompatibilities
Requirements for storage areas and containers: Cylinders should be stored upright and firmly secured to pre-vent falling or being knocked over. Separate full containers from empty containers. Do not store near combustible materials. Avoid area where salt or other corrosive materials are present. Keep in properly labelled containers. Keep in a cool, well-ventilated place. Keep away from direct sunlight. Store in accordance with the particular national regulations.
Advice on common storage: Do not store with the following product types:
Self-reactive substances and mixtures
Organic peroxides
Oxidizing agents
Flammable liquids
Flammable solids
Pyrophoric liquids
Pyrophoric solids
Self-heating substances and mixtures
Substances and mixtures, which in contact with water, emit flammable gases
Acutely toxic substances and mixtures
Substances and mixtures with chronic toxicity
Storage period: > 10 yr
Recommended storage temperature: < 52 °C
Further information on storage stability: The product has an indefinite shelf life when stored properly.

Transport information

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Marine transport (UN RTDG/IMDG)

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Exposure controls / personal protection

Engineering measures
Ensure adequate ventilation, especially in confined areas.
Minimize workplace exposure concentrations.
Personal protective equipment
Eye protection: Wear the following personal protective equipment:
Chemical resistant goggles must be worn.
Equipment should conform to BS EN 166

Hand protection
Remarks: Take note that the product is extremely cold, which may im-pact the selection of hand protection. Wash hands before breaks and at the end of workday.
Skin and body protection: Skin should be washed after contact.
Respiratory protection : If adequate local exhaust ventilation is not available or exposure assessment demonstrates exposures outside the recommended guidelines, use respiratory protection.
Equipment should conform to BS EN 14387
Filter type : Organic gas and low boiling vapour type (AX)
Protective measures : Wear cold insulating gloves/ face shield/ eye protection.

Eye protection: Wear safety glasses or coverall chemical splash goggles. Eye protection complying with EN 166. or ANSI Z87.1. Additionally wear a face shield where the possibility exists for face contact due to splashing, spraying or airborne contact with this material.

Hand protection
Material: Leather gloves
The suitability for a specific workplace should be discussed with the producers of the protective gloves.
Material: Low temperature resistant gloves
Protective gloves complying with EN 374. or US OSHA guidelines
The choice of an appropriate glove does not only depend on its material but also on other quality features and is different from one producer to the other. Please observe the instructions regarding permeability and breakthrough time which are provided by the supplier of the gloves. Also take into consideration the specific local conditions under which the product is used, such as the danger of cuts, abrasion, and the contact time.

Skin and body protection: Wear suitable protective equipment. Wear as appropriate: impervious clothing
Protective measures: Self-contained breathing apparatus (SCBA) is required if a large release occurs. The type of protective equipment must be selected according to the concentration and amount of the substance at the specific workplace.

Hygiene measures: Handle in accordance with good industrial hygiene and safety practice.

Respiratory protection: For rescue and maintenance work in storage tanks use self-contained breathing apparatus. Vapours are heavier than air and can cause suffocation by reducing oxygen available for breathing. Respiratory protection complying with EN 137.

Stability and reactivity

Reactivity: Not classified as a reactivity hazard.
Chemical stability: Stable if used as directed. Follow precautionary advice and avoid incompatible materials and conditions
Possibility of hazardous reactions
Hazardous reactions: Can react with strong oxidizing agents.

Conditions to avoid: This substance is not flammable in air at temperatures up to 100 °C (212 °F) at atmospheric pressure. However, mixtures of this substance with high concentrations of air at elevated pressure and/or temperature can become combustible in the presence of an ignition source. This substance can also be-come combustible in an oxygen enriched environment (oxygen concentrations greater than that in air). Whether a mixture containing this substance and air, or this substance in an ox-ygen enriched atmosphere become combustible depends on the inter-relationship of 1) the temperature 2) the pressure, and 3) the proportion of oxygen in the mixture. In general, this substance should not be allowed to exist with air above at-mospheric pressure or at high temperatures; or in an oxygen enriched environment. For example this substance should NOT be mixed with air under pressure for leak testing or other purposes.
Heat, flames and sparks.
Incompatible materials
Materials to avoid: Oxidizing agents
Hazardous decomposition products: No hazardous decomposition products are known

Disposal considerations

Waste treatment methods
Product: Dispose of in accordance with local regulations.
According to the European Waste Catalogue, Waste Codes are not product specific, but application specific.
Waste codes should be assigned by the user, preferably in discussion with the waste disposal authorities.

Contaminated packaging : Empty containers should be taken to an approved waste handling site for recycling or disposal.
Empty pressure vessels should be returned to the supplier.
If not otherwise specified: Dispose of as unused product.