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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

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Diss Factsheets

Ecotoxicological information

Endpoint summary

Administrative data

Description of key information

Additional information

Short-term aquatic toxicity testing on Polycat 77 was conducted in fish (Brachydanio rerio) and aquatic algae.

Long term testing was conducted in aquatic invertebrates (Daphnia magna). 

An algal growth inhibition assay (Desmodesmus subspicatus) and an activated sludge respiration inhibition assay were conducted on a supporting substance (N,N-bis[3-(dimethylamino)propyl]-N',N'-dimethylpropan-1,3-diamine; CASRN 33329-35-0), based upon read-across from a supporting substance (structural analogue or surrogate)

The lowest aquatic L(E)C50was observed in Daphnia magna, (EC50= 2.2 mg/L). 

Long-term testing in fish was not conducted; According to REACH Annex XI, 1.2., long-term testing for toxicity to fish is not necessary as there are sufficient available data for risk assessment. There are three reliable acute tests for aquatic toxicity for three trophic levels (fish, Daphnia, algae) available and, in addition, two long-term tests for two trophic levels (Daphnia and algae). Comparing the effect concentrations for the three trophic levels, fish are not the most sensitive species. The most sensitive species is Daphnia. A long-term fish test is not expected to improve the information on aquatic toxicity or provide lower effect concentrations. The available data are adequate for the purpose of classification and labelling and/or risk assessment as hazardous to the environment. Therefore, long-term aquatic toxicity testing was not indicated.

An acute toxicity study on the effects of the substance on zebra fish (Brachydanio rerioHAM. and BUCH.) was conducted. Based on measured concentrations, the 96-h LC50 was reported as 92.5 mg/L. Mortality occurred first at the concentration of 46.4 mg/L (nominal). Other substance-related effects were the symptoms of apathy, tumbling, and swimming near the water surface. The NOEC was reported as 21.5 mg/L (nominal). Based on the arithmetic mean values of the analytically detected concentrations after 96 hours, the LC50 was reported at about 92.5 mg/L. The pH adjustment of a parallel group with the highest nominal concentration (464 mg/L) did not significantly reduce mortality and toxic signs.

In an Algal Growth Inhibition Test with Raphidocelis subcapitata according to OECD 201, the 72hr EC50 for both growth rate and yield was determined as 34.99 mg/L. The NOEC for both growth rate and yield was determined as 25 mg/L.

In a semi-static Daphnia magna Reproduction Test according to OECD 211, the 21day EC50 for reproduction was determined as 10.3 mg/L. The NOEC for reproduction was determined as 2.2 mg/L.