Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Skin irritation / corrosion

Currently viewing:

Administrative data

skin irritation / corrosion
other: Determination of pH-value
Type of information:
experimental study
Adequacy of study:
weight of evidence
Study period:
Between 31-05-2012 - and 14-06-2012
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: Well reported determination of pH value according to accepted scientific methods.

Data source

Reference Type:
study report
Report date:

Materials and methods

Principles of method if other than guideline:
Electrochemic determination of pH
The determination of the pH-value was in compliance with TIAG standard operating procedures AANC Determination of the pH value (2012).
GLP compliance:

Test material

Constituent 1
Chemical structure
Reference substance name:
Cerium trichloride
EC Number:
EC Name:
Cerium trichloride
Cas Number:
Molecular formula:
cerium trichloride

Test animals

other: Not applicable
other: Not applicable
Details on test animals or test system and environmental conditions:
Not applicable

Test system

Type of coverage:
other: Not applicable
Preparation of test site:
other: Not applicable
not specified
Details on study design:
Preparation of test item:
At first, a 10% solution of the test item was prepared by stirring 10 g sample material with 90g H2O dem. (Milli-Q water - Type 1 water grade) for 30 minutes and then adjusting it to a temperature of 20°C.

Calibration of the pH-meter:
Prior to the measurement the pH meter was checked and calibrated with a buffer solution in the expected measurement range. The pH meter was calibrated via a 3-point calibration. The slope of the electrode and the result of the control buffer were either listed in the "Prüfmittelkontrollblatt" or "calibration report". The electrode was rinsed with H2O dem., wiped dry and immersed for measurement into the solution.

Determination of the pH-value of the test item:
The pH is determined 3 times from a 10% solution of the test item under continuous stirring. The measured pH was protocolled.

Apparatus and auxiliary material:
- Analytical scales with an accuracy of 0.01g
- pH-meter with pH electrode or 809 Titrando v. Metrohm
- Buffer solutions 1.09, 4.01, 6.00
- Magnetic stirrer with magnetic stir bar
- Beakers
- Flask
- Water bath
- Pipettes
- Milli-Q water

Results and discussion

In vivo

Remarks on result:
other: The substance is considered not to be corrosive
Irritant / corrosive response data:
Not corrosive

Any other information on results incl. tables

Since the determined pH-value was 4.58 a determination of the acid reserve was not applicable.

Applicant's summary and conclusion

Interpretation of results:
other: not corrosive
The pH value was determined to be 4.58. Because of this pH value a determination of the acid reserve was not applicable.