Registration Dossier

Administrative data

Description of key information

Key value for chemical safety assessment

Skin sensitisation

Endpoint conclusion
Endpoint conclusion:
adverse effect observed (sensitising)
Additional information:

The results presented in the skin sensitisation paper demonstrate further that the LLNA provides quantitative information on skin sensitising potency which is predictive of allergenic potency in humans. Such data promises to be a valuable tool for hazard characterization and for risk assessment.

Based on the results of this study the Cyclamen Aldehyde is classified as a weak sensitiser (R43) and Skin Sens.1.


Migrated from Short description of key information:
Based on the results of this study the Cyclamen Aldehyde is classified as a weak sensitiser (R43) and Skin Sens.1.

Justification for selection of skin sensitisation endpoint:
the LLNA provides quantitative information on skin sensitising potency which is predictive of allergenic potency in humans.

Respiratory sensitisation

Endpoint conclusion
Endpoint conclusion:
no study available

Justification for classification or non-classification

the LLNA provides quantitative information on skin sensitising potency which is predictive of allergenic potency in humans.

Based on the results of this study the Cyclamen Aldehyde is classified as a weak sensitiser (R43) and Skin Sens.1.