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Ecotoxicological information

Long-term toxicity to aquatic invertebrates

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Description of key information

Testing is not scientifically justified as this substance is hydrolytically unstable. Therefore, the long-term toxicity of the main decomposition product Exxal 8  is used as a key value.

Key value for chemical safety assessment

Fresh water invertebrates

Fresh water invertebrates
Effect concentration:
1.6 mg/L

Additional information

When this substance comes in contact with water or moisture, a complete hydrolysis will take place with no significant reaction products other than Exxal 8 (alcohols, C7 -C9-iso, C8-rich) and hydrated titanium dioxide (key study on hydrolysis Brekelmans M.J.C. 2013). This organic decomposition product is readily biodegradable and not bioaccumulative (log Kow value 3.2 and BCF 15.2 L/kg). The CSA indicates that toxicity of this substance is similar to the main degradation product Exxal 8. Key studies short-term toxicity to daphnia and algae conducted for the substance justify that this organometallic titanate hydrolyses during toxicity testing and the aquatic toxicity is similar to the alcohol released in water. Therefore, the long-term toxicity study on invertebrates is unjustified, and the key value for CSA is obtained from the most reliable existing data on the decomposition product (Exxal 8). According to Cash G et al (1999) & US EPA – OPPT (2000), the estimated 16-d EC50 of Exxal 8 to Daphnia magna in freshwater is 1.6 mg/l based on calculated Kow value. This study was well reported and considered as reliable to be used as a weight of evidence to evaluate the long-term toxicity of the target substance in freshwater.

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