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Short-term toxicity to aquatic invertebrates

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Description of key information

The 48-hour EC50 (immobilisation) to Daphnia magna, 41 mg/l (95 % CI, 37 to 49 mg octyl alcohols isomers/l) based on the measured octyl alcohol isomers concentrations as per OECD 202. This value represents an approximate test item concentration of 74 mg/l.

Key value for chemical safety assessment

Fresh water invertebrates

Fresh water invertebrates
Effect concentration:
74 mg/L

Additional information

The acute toxicity test performed for this substance identifies that toxicity of this substance are related to the degradation products due to the rapid hydrolysis which takes place immediately after test substance is introduced to water solution. Due to the rapid hydrolysis in aqueous test media, the degradation products isooctyl alcohol isomers (Exxal 8) and hydrated titanium oxides) toxicity to the freshwater invertebrates (D.magna) was investigated based on the measured concentrations of mixture of isooctyl alcohol isomers (48 -h EC50; 41 mg/l) and the equivalent test item concentrations (48 -h EC50; 74 mg/l). The key study was conducted according to OECD 202 in accordance with GLP.

Supporting studies on the toxicity of octyl alcohol isomers justifies that the toxicity of this target substance is similar to the toxicity of the degradation product (Exxal 8). The 48-hour EL50 (mobility) was 31.8 mg/l based on nominal loading conducted by using the method US EPA 660/3-75-009 (Union Carbide 1980).

Results of this key study do not lead to the classification of the substance as toxic to aquatic organisms in accordance with the criteria set out in Directive 67/548/EC and Regulation (EC) 1272/2008. This toxicity study is classified as reliable without restrictions and satisfies the guideline requirements for the acute invertebrate toxicity study.