Registration Dossier
Registration Dossier
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EC number: 224-207-2 | CAS number: 4246-51-9
Toxicity to soil microorganisms
Administrative data
Link to relevant study record(s)
Description of key information
No data available.
Key value for chemical safety assessment
Additional information
No studies on soil microorganisms are available for 3,3'-oxybis(ethyleneoxy)bis(propylamine) (CAS 4246-51-9). In Annex X section 9.4 of Regulation (EC) No 1907/2006, it is laid down that tests on terrestrial organisms shall be proposed by the registrant if the chemical safety assessment indicates the need to investigate further the effects on terrestrial organisms. The choice of the appropriate tests depends on the outcome of the chemical safety assessment. In particular for substances that have a high potential to adsorb to soil or that are very persistent, the registrant shall consider long-term toxicity testing instead of short-term. According to Annex X section 9.4 of Regulation (EC) No 1907/2006, those studies do not need to be conducted if direct or indirect exposure of the soil compartment is unlikely. The available data indicate that the substance is not very adsorptive (log Koc < 3; see IUCLID chapter 5.4.1) or bioaccumulative (log Kow < 3; see IUCLID chapter 5.3.1). Furthermore, the distribution modelling indicates that the main target for environmental distribution will be water (see IUCLID chapter 5.4.3). Therefore, exposure of terrestrial organisms is unlikely. In addition, the substance is not a PBT or vPvB substance and the risk assessment results in Risk Characterization Ratios (RCRs) far below 1 for all compartments. Consequently, no test on soil microorganisms is performed. The equilibrium partitioning method has been used to assess the hazard potential for soil organisms.
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