Registration Dossier
Registration Dossier
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EC number: 200-945-0 | CAS number: 76-22-2
Acute Toxicity: inhalation
Administrative data
- Endpoint:
- acute toxicity: inhalation
- Type of information:
- experimental study
- Adequacy of study:
- weight of evidence
- Reliability:
- 2 (reliable with restrictions)
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 003
Materials and methods
Test guideline
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- OECD Guideline 403 (Acute Inhalation Toxicity)
- GLP compliance:
- no
- Test type:
- fixed concentration procedure
Test material
- Reference substance name:
- Bornan-2-one
- EC Number:
- 200-945-0
- EC Name:
- Bornan-2-one
- Cas Number:
- 76-22-2
- Molecular formula:
- C10H16O
- IUPAC Name:
- 1,7,7-trimethylbicyclo[2.2.1]heptan-2-one
- Test material form:
- solid: crystalline
Constituent 1
Test animals
- Species:
- rat
- Strain:
- Sprague-Dawley
- Sex:
- male/female
Administration / exposure
- Route of administration:
- inhalation: dust
- Type of inhalation exposure:
- whole body
- Vehicle:
- not specified
- Duration of exposure:
- ca. 2 h
- Concentrations:
- 1000mg/m3, 2150 mg/m3, 4640mg/m3, 10000mg/m3
- No. of animals per sex per dose:
- 5 females, 5 males
Results and discussion
Effect levels
- Sex:
- male/female
- Dose descriptor:
- LC50
- Effect level:
- > 10 000 mg/m³ air
- Based on:
- test mat.
- Clinical signs:
- other: na
- Body weight:
- 180-220g
Applicant's summary and conclusion
- Interpretation of results:
- Toxicity Category IV
- Remarks:
- Migrated information Criteria used for interpretation of results: EU
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