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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Description of key information

Oral:

In an acute oral toxicity study similar to OECD 401 guideline, a LD50 of above 5000 mg/kg bw was determined (Stahl, 1980).

Key value for chemical safety assessment

Acute toxicity: via oral route

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed
Dose descriptor:
discriminating dose
Value:
5 000 mg/kg bw

Acute toxicity: via inhalation route

Endpoint conclusion
Endpoint conclusion:
no study available
Quality of whole database:
.

Acute toxicity: via dermal route

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed
Dose descriptor:
discriminating dose
Value:
2 000 mg/kg bw

Additional information

Acute toxicity: via oral route
In a study similar to OECD 401 guideline on the analogue substance the acute oral toxicity of the test substance following a single oral administration in Sprague-Dawley rats was investigated (Stahl, 1980). Two groups of 10 fasted animals (5 animals per sex and dose) were exposed to 2150 and 5000 mg/kg bw of unchanged test substance and observed for 14 days. No mortality occurred. Accordingly, the acute oral LD50 of the test substance after single oral administration to rats is > 5000 mg/kg bw.

Justification for classification or non-classification

Classification, Labelling, and Packaging Regulation (EC) No 1272/2008
The available experimental test data are reliable and suitable for classification purposes under Regulation 1272/2008 (CLP). As a result the test item is not considered to be classified for acute oral or dermal toxicity under Regulation (EC) No 1272/2008, as amended for the tenth time in Regulation (EU) No 2017/776.

Based on the read across considerations tha target substance is not classified for acute toxicity