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Administrative data

Description of key information

Oral:

In an acute oral toxicity study similar to OECD 401 guideline, a LD50 of above 5000 mg/kg bw was determined (Stahl, 1980).

Key value for chemical safety assessment

Acute toxicity: via oral route

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed
Dose descriptor:
discriminating dose
Value:
5 000 mg/kg bw

Acute toxicity: via inhalation route

Endpoint conclusion
Endpoint conclusion:
no study available
Quality of whole database:
.

Acute toxicity: via dermal route

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed
Dose descriptor:
discriminating dose
Value:
2 000 mg/kg bw

Additional information

Acute toxicity: via oral route
In a study similar to OECD 401 guideline on the analogue substance the acute oral toxicity of the test substance following a single oral administration in Sprague-Dawley rats was investigated (Stahl, 1980). Two groups of 10 fasted animals (5 animals per sex and dose) were exposed to 2150 and 5000 mg/kg bw of unchanged test substance and observed for 14 days. No mortality occurred. Accordingly, the acute oral LD50 of the test substance after single oral administration to rats is > 5000 mg/kg bw.

Justification for classification or non-classification

Classification, Labelling, and Packaging Regulation (EC) No 1272/2008
The available experimental test data are reliable and suitable for classification purposes under Regulation 1272/2008 (CLP). As a result the test item is not considered to be classified for acute oral or dermal toxicity under Regulation (EC) No 1272/2008, as amended for the tenth time in Regulation (EU) No 2017/776.

Based on the read across considerations tha target substance is not classified for acute toxicity