Registration Dossier
Registration Dossier
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 257-804-1 | CAS number: 52277-71-1
Endpoint summary
Administrative data
Description of key information
Oral:
In an acute oral toxicity study similar to OECD 401 guideline, a LD50 of above 5000 mg/kg bw was determined (Stahl, 1980).
Key value for chemical safety assessment
Acute toxicity: via oral route
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed
- Dose descriptor:
- discriminating dose
- Value:
- 5 000 mg/kg bw
Acute toxicity: via inhalation route
Endpoint conclusion
- Endpoint conclusion:
- no study available
- Quality of whole database:
- .
Acute toxicity: via dermal route
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed
- Dose descriptor:
- discriminating dose
- Value:
- 2 000 mg/kg bw
Additional information
Acute toxicity: via oral route
In a study similar to OECD 401
guideline on the analogue substance the acute oral toxicity of the test
substance following a single oral administration in Sprague-Dawley rats
was investigated (Stahl, 1980). Two groups of 10 fasted animals (5
animals per sex and dose) were exposed to 2150 and 5000 mg/kg bw of
unchanged test substance and observed for 14 days. No mortality
occurred. Accordingly, the acute oral LD50 of the test substance after
single oral administration to rats is > 5000 mg/kg bw.
Justification for classification or non-classification
Classification, Labelling, and Packaging
Regulation (EC) No 1272/2008
The available experimental test data are reliable and suitable for
classification purposes under Regulation 1272/2008 (CLP). As a result
the test item is not considered to be classified for acute oral or
dermal toxicity under Regulation (EC) No 1272/2008, as amended for
the tenth time in Regulation (EU) No 2017/776.
Based on the read across considerations tha target substance is not classified for acute toxicity
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
