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Short-term toxicity to fish

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Description of key information

DEAPA is considered as slightly harmful to fish.

Key value for chemical safety assessment

Fresh water fish

Fresh water fish
Dose descriptor:
LC50
Effect concentration:
146.6 mg/L

Additional information

Diethylaminopropylamine (DEAPA) acute toxicity to Leuscisus idus has been investigated according to German industrial standard test guideline DIN 38412 part 15. LC50_96h was determined to be 146.6 mg/L when DEAPA was not neutralized. But no effect was observed at the highest concentration tested (464 mg/L) when neutralized. The result of the study suggests that the toxicity of DEAPA is related to the increase of the medium pH but not to a specific mode of toxic action. This low toxicity is supported by the value estimated by QSAR models. 


The concentrations were not measured in the vessels during the test but DEAPA is expected to be stable in water. Indeed, DEAPA is miscible in water, its vapor pressure is low and it is not subject to hydrolysis. Therefore there are no cause of significant deviation from nominal to real substance concentrations.