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Ecotoxicological information

Short-term toxicity to fish

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Description of key information

Methylene bis(dibutyldithiocarbamate) gave a 96-Hour LC50 value of greater than 0.060 mg /L. The NOEC was 0.060 mg/L (Safepharm Laboratories, 2004).
The test material is known to possess low water solubility (0.243 mg/l at 20 ± 5 ºC). In the absence of any evidence of toxicity, and taking into consideration the difficulties in water solubility, it is considered that no evidence of toxicity is seen at the limit of solubility.

Key value for chemical safety assessment

LC50 for freshwater fish:
0.06 mg/L

Additional information

In an OECD 203 study, conducted to GLP, based on the mean measured test concentrations of the centrifuged test media the acute toxicity of the test material to rainbow trout, methylene bis(dibutyldithiocarbamate) gave a 96-Hour LC50 value of greater than 0.060 mg /L. The NOEC was 0.060 mg/L (Safepharm Laboratories, 2004).

No mortality was observed during the test. The test was conducted using dimethylforamide to pre-dissolve the test material before dilution in test media. When analysed test concentrations were far lower than what was theoretically created, indicating that there were difficulties stemming from water solubility of the test material. The test material is known to possess low water solubility (0.243 mg/l at 20 ± 5 ºC). In the absence of any evidence of toxicity, and taking into consideration the difficulties in water solubility, it is considered that no evidence of toxicity is seen at the limit of solubility.