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Physical & Chemical properties

Water solubility

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water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
From 20 November to 13 December 2002
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
according to guideline
OECD Guideline 105 (Water Solubility)
GLP compliance:
Type of method:
flask method
Water solubility:
0 g/L
20 °C
>= 5.6 - <= 6
Remarks on result:
other: Range of 6.16E-05 to 3.16E-04 g/L
Details on results:
Preliminary test:
The preliminary estimate of water solubility was 5.55E-06 g/L.

Definitive test:
The mean concentration of test material in the sample solutions is 2.43E-04 g/L at 20.0±0.5 deg. C, range of 6.16E-05 to 3.16E-04 g/L.
The water solubility of the test item has been determined to be 2.43E-04 g/L of solution at 20.0±0.5 deg. C.

Description of key information

The test item is determined to have a water solubility of 0.243 mg/L at 20 deg. C ± 0.5 (SafePharm, 2003).

Key value for chemical safety assessment

Water solubility:
0.243 mg/L
at the temperature of:
20 °C

Additional information