Registration Dossier
Registration Dossier
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EC number: 201-170-0 | CAS number: 79-03-8
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
Parent compound propionyl chloride: no data.
Hydrolysis product propionic acid: With high probability acutely not harmful to aquatic invertebrates after pH-adjustment.
Hydrolysis product HCl: Acutely very toxic for aquatic invertebrates (pH-dependent)
Key value for chemical safety assessment
Additional information
Parent compound propionyl chloride:
No data are available for propionyl chloride (CAS 79-03-8). The substance rapidly decomposes in water and forms HCl (CAS 7647 -01 -0) and propionic acid (CAS 79 -09 -4). Therefore, the short-term toxicity to aquatic invertebrates is assessed on the basis of data on propionic acid and the structurally similar substance calcium propionate (CAS 4075-81-4).
Hydrolysis product propionic acid:
For calcium propionate the 48-h EC50 value on D. magna is >500 mg/L [BASF AG, 1989]. The analogous substance was chosen in order to avoid the pH dependent effect of pure propionic acid solution. Therefore, an acute test with propionic acid was not taken into account (48 -h EC50 = 22.7 mg/L; OECD SIDS draft, 2008) although resulting in lower effect values as it is assumed that the effects due to the low pH of the test solution might have occured.
Hydrolysis product hydrochloric acid (HCl):
The hydrolysis product hydrochloric acid (HCl) was tested in a semi-static acute toxicity test according to OECD 202 with Daphnia magna. The 48-h EC50 was 0.492 mg/L (acid equivalent to pH 5.3; OECD, 2002).
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