Registration Dossier
Registration Dossier
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EC number: 209-520-4 | CAS number: 583-78-8
Bioaccumulation: aquatic / sediment
Administrative data
- Endpoint:
- bioaccumulation in aquatic species: fish
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: peer reviewed in HSDB - last update 2009-08-20
Data source
Reference
- Reference Type:
- other: Database
- Title:
- Chemical Risk Information Platform (CHRIP). Biodegradation and Bioconcentration
- Author:
- NITE
- Year:
- 2 009
- Bibliographic source:
- Tokyo, Japan: Natl Inst Tech Eval. Available at http://www.safe.nite.go.jp/english/db.html as of Feb. 10, 2009
Materials and methods
- Principles of method if other than guideline:
- guideline not reported
- GLP compliance:
- not specified
Test material
- Reference substance name:
- 2,5-dichlorophenol
- EC Number:
- 209-520-4
- EC Name:
- 2,5-dichlorophenol
- Cas Number:
- 583-78-8
- Molecular formula:
- C6H4Cl2O
- IUPAC Name:
- 2,5-dichlorophenol
- Reference substance name:
- Phenol, 2,5-dichloro-
- IUPAC Name:
- Phenol, 2,5-dichloro-
- Test material form:
- not specified
Constituent 1
Constituent 2
- Radiolabelling:
- not specified
Test solutions
- Vehicle:
- not specified
Test organisms
- Test organisms (species):
- Cyprinus carpio
Study design
- Route of exposure:
- aqueous
- Test type:
- static
- Water / sediment media type:
- natural water: freshwater
- Total exposure / uptake duration:
- 6 wk
Test conditions
- Nominal and measured concentrations:
- 1st Concentration area 30ppb, 2nd Concentration area 3ppb
RANGE-FINDING/PRELIMINARY STUDY Test concentrations: LC50(48hr), 4.2ppm, Rice fish(Oryzias latipes)
Results and discussion
Bioaccumulation factoropen allclose all
- Type:
- BCF
- Value:
- 4 - 35 dimensionless
- Basis:
- not specified
- Remarks on result:
- other: Conc.in environment / dose:30 ppb
- Type:
- BCF
- Value:
- 4.8 - 16 dimensionless
- Basis:
- not specified
- Remarks on result:
- other: Conc.in environment / dose:3 ppb
Applicant's summary and conclusion
- Validity criteria fulfilled:
- not specified
- Conclusions:
- This BCF suggest the potential for bioconcentration in aquatic organisms is low
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