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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
acute toxicity: other routes
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)

Data source

Referenceopen allclose all

Reference Type:
review article or handbook
Title:
RTECS Number: XU8227250
Author:
RTECS database
Year:
2012
Bibliographic source:
RTECS(Registry of Toxic Effects of Chemical Substances);Summary Tables of Biological Tests,"National Research Council Chemical-Biological Coordination Center.(National Academy of Science Library,2101 Constitution Ave.,NW,Washington,DC 20418) V.6,230,1954
Reference Type:
other: Authoritative data base
Title:
GCID: 502736
Author:
ACToR database
Year:
2011
Bibliographic source:
ACToR (Aggregated Computational Toxicology Resource); Summary Tables of Biological Tests, National Research Council Chemical- Biological Coordination Center. Vol. 6, Pg. 230, 1954.

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
other:
Principles of method if other than guideline:
Data is from RTECS, ACToR.
GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
2-nitro-p-toluidine
EC Number:
201-924-9
EC Name:
2-nitro-p-toluidine
Cas Number:
89-62-3
Molecular formula:
C7H8N2O2
IUPAC Name:
4-methyl-2-nitroaniline
Details on test material:
- Name of test material: 2-nitro-p-toluidine
- Molecular formula: C7H8N2O2
- Molecular weight: 152.15
- Substance type: organic

Test animals

Species:
mouse
Strain:
not specified
Sex:
not specified

Administration / exposure

Route of administration:
intraperitoneal
Vehicle:
not specified
Control animals:
not specified

Results and discussion

Effect levels
Sex:
not specified
Dose descriptor:
other: LD
Effect level:
> 500 other: mg/kg
Based on:
test mat.
Remarks on result:
other: other details not available

Applicant's summary and conclusion

Conclusions:
Acute intraperitoneal toxicity value of 2-nitro-p-toluidine to mouse is found to be LD: > 500mg/kg.
Executive summary:

Acute intraperitoneal toxicity value of 2-nitro-p-toluidine to mouse is found to be LD: > 500mg/kg.