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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Short-term toxicity to fish

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Administrative data

Link to relevant study record(s)

Description of key information

Based on the weight of evidence approach, the lethal concentration (LC50) value of 2-nitro-p-toluidine in various species of fish was found to range between 5 to 10 mg/L., with one study indicating an LC50 value of 11.1 mg/L. Thus, it is concluded that the chemical 2-nitro-p-toluidine shall exhibit aquatic toxicity to fish in the chronic category 2. The majority LC50 value of 5 mg/L has been considered for the chemical safety assessment.

Key value for chemical safety assessment

Fresh water fish

Fresh water fish
Effect concentration:
5 mg/L

Additional information

Based on the weight of evidence approach, the lethal concentration (LC50) value of 2-nitro-p-toluidine in various species of fish was found to range between 5 to 10 mg/L., with one study indicating an LC50 value of 11.1 mg/L. Thus, it is concluded that the chemical 2-nitro-p-toluidine shall exhibit aquatic toxicity to fish in the chronic category 2. The summary of the various weight of evidence studies is presented below:

S. No

End point

Value in mg/L

Duration

Species

1

LC50

10

4 to 7 hr

Oncorhynchus tschawytscha

2

LC50

5

3 hr

Lepomis macrochirus

3

LC50

5

3 hr

Carassius auratus

4

LC50

10

1-2 hr

Oncorhynchus kisutch

5

LC50

5

30 min

Oncorhynchus mykiss

6

LC50

11.164

96 hr

Fish (species not specified)