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Short-term toxicity to aquatic invertebrates

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Description of key information

48 h EC50: 40 mg/L

Key value for chemical safety assessment

EC50/LC50 for freshwater invertebrates:
40 mg/L

Additional information

In the Klimisch 1 GLP study from Kimmel (2013) the acute toxicity of Butanedioic acid, sulfo-, 4-C12-14-alkyl esters, disodium salts on Daphnia magna was determined in an 48 hour static test according to OECD 202 and EU method C.2. The test was performed with concentrations of 6.25, 12.5, 25, 50 and 100 mg test item/L. After 48 hours 0, 0, 0. 0, 90 and 100 % immobilization was observed in the control and at test concentrations of 0.6.25, 12.5, 25, 50 and 100 mg test item/L, respectively. Analytical measurements of the biologically relevant test concentrations of 1.8, and 4 mg sulfosuccinate/L confirmed that the test solutions were correctly dosed and statble throughour the exposure period. Therefore the data were evaluated based on nominal concentrations. The EC50 is 40 mg test item /L.

The results are considered relevant and reliable for the risk assessment.