Registration Dossier
Registration Dossier
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EC number: 280-084-5 | CAS number: 82985-35-1
Endpoint summary
Administrative data
Description of key information
Additional information
Short term tests with bis(trimethoxysilylpropyl)amine (CAS 82985-35-1), are available for three trophic levels i.e. fish, aquatic invertebrates and algae. The substance hydrolyses rapidly in contact with water with a half-life = 6.9 h (at neutral pH and room temperature). The hydrolysis products are bis(trihydroxysilylpropyl)amine and methanol. Therefore the tested organisms were primarily exposed to the hydrolysis products.
All aquatic studies were performed according to international guidelines and GLP standards. Since the substance acts slightly as a base in contact with water the tests were conducted in two parallels with unadjusted and with adjusted pH. Algae turned out to be the most sensitive species with an ErC50 (72 h) of 36 mg/L and an ErC10 (72 h) of 8.3 mg/L (nominal). For fish and daphnia an LC50 (96 h) and an EC50 (48 h) of > 100 mg/L (nominal) were determined, respectively.
Furthermore a study is available testing the respiration inhibition of the substance on activated sludge. The study resulted in an EC10 (3 h) of 270 mg/L (nominal).
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