Registration Dossier
Registration Dossier
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EC number: 211-720-1 | CAS number: 691-37-2
Endpoint summary
Administrative data
Description of key information
The acute oral median lethal dose (LD50) of 4-methyl-1-pentene was >2000mg/kg (OECD 423).
Key value for chemical safety assessment
Acute toxicity: via oral route
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed
- Dose descriptor:
- LD50
- Value:
- 2 000 mg/kg bw
Additional information
Acute oral:
In the key study oral toxicity was assessed using the acute tox class method. The study was performed according to GLP and OECD Guideline 423. The acute oral median lethal dose (LD50) of 4-methyl-1-pentene was >2000mg/kg.
Acute dermal and inhalation:
Investigation of acute toxicity via the inhalation and dermal route is unnecessary because the substance is imported into Europe in polymerised (non-available) form. Furthermore company specific analytical data demonstrates that the amount of residual monomer is present at a very low concentration of 14-20ppm as 4-methylpent-1-ene.
Justification for selection of acute toxicity – oral endpoint
The study was performed according to GLP and OECD Guideline 423
Justification for classification or non-classification
The acute oral median lethal dose (LD50) of 4-methyl-1-pentene was >2000mg/kg, therefore according to Regulation (EC) 1272/2008 the substance is not considered to be classified.
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