Registration Dossier
Registration Dossier
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EC number: 701-363-4 | CAS number: -
Endpoint summary
Administrative data
Description of key information
Additional information
Acutely toxic to aquatic organisms. The inhibition of the degradation activity of activated sludge is not anticipated when introduced in appropriate low concentrations.
This aquatic toxicity assessment was based on the following data:
The registration item was found to cause lethal and sublethal effects to zebrafish after
96 hours at a nominal loading of 5.50 mg/L and higher. The LL5o after 96 hours was 3.71
(2.50 - 5.50) mg test item/L. Based on this result the test substance is considered to be acutely toxic to fish.
In a GLP guideline studies according to OECD 202, an EL50 of 101 mg/L was obtained for the registration item. Therefore, the test substance is considered to be with high probability acutely not harmful to aquatic invertebrates.
The toxicity of the structurally related substance CAS 118800-30-9 to aquatic algae was investigated in a GLP guideline study according to OECD 201. In this study, an acute EC50 (96h) of 27 mg/L for the growth rate of Desmodesmus subspicatus as well as an EC10 (72h) value of 8.97 mg/L was determined (BASF AG 98/0634/60/1, 1998). These results are considered to be adaptable for the test substance due to the structural similarities and identical core-molecules of those substances. Based on these values the test substance is considered to be acutely not harmful to aquatic invertebrates. Long-lasting effects on algeae are not expected.
Data of the structurally related molecule CAS 173011-06-8 are available for the toxicity assessment of the test substance to microorganisms. CAS 173011-06-8: In a short-term respiration test similar to OECD 209 an EC20 of approx. 1000 mg/L was determined(BASF AG 92/1991/08/11983, 1992). Additionally, in an oxygen consumption test according to DIN 38412 part 27 using Pseudomonas putida an EC10 of >= 1000 mg/L was determined (BASF AG 92/1991/71/1, 1993). These results are considered to be adaptable for the test substance due to the structural similarities and the identical core-molecules. Based on these values the inhibition of the degradation activity of activated sludge is not anticipated when introduced in appropriate low concentrations.
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