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EC number: 223-989-2 | CAS number: 4156-21-2
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
In this study no inhibition on growth of the freshwater green alga Desmodesmus subspicatus was found after 72 hours exposure to the test item Active substance of Granofin Easy F-90 liq in aqueous solution. The NOEC for inhibition of specific growth rate and yield after 72 hours was 143 mg test item/L, corresponding to 100 mg/L of the main component. All effect levels are given based on the nominal concentration of Active substance of Granofin Easy F-90 liq in aqueous solution which has been analytically verified by HPLC-DAD.
Key value for chemical safety assessment
- EC10 or NOEC for freshwater algae:
- 143 mg/L
Additional information
The toxicity ofActive substanceof Granofin Easy F-90 liq inaqueous solution to the unicellular freshwater green algaDesmodesmus subspicatuswas determined according to the principles of OECD 201atDr.U.Noack-Laboratorienin 31157 Sarstedt, Germanyfrom to , with the definitive exposure phase from 2012-03-27 to 2012-03-30.The aim of the study was to assess the effects on growth rate and yield over a period of 72 hours.
The study was conducted under static conditions with an initial cell density of 4910 cells/mL.Based on a preliminary range finding test the limit concentration of 143 mg test item /L, corresponding to 100 mg/L main component,was tested.Sixreplicates were tested for the limit concentration and the control.Environmental conditionswere determined to be within the acceptable limits.
The limit concentration and the control were analysed by HPLC-DAD after (fresh media) and 72 h (old media).
The measured concentration of the test item in the fresh media (0 h) was 101 %. The test item concentration in the old media (72 h) was 83 %.
All effect values are based on the nominal concentration of the main component as well as the test item.
NOEC, LOEC, EC - values of Active substanceof Granofin Easy F-90 liq inaqueous solution (0-72 hours)
based on nominal concentration of the main component and test item [mg/L]
Inhibition of Growth Rate |
||
Main Component [mg/L] |
Test Item [mg/L] |
|
NOEC |
100 |
143 |
LOEC |
> 100 |
> 143 |
ErC10 |
> 100 |
> 143 |
ErC20 |
> 100 |
> 143 |
ErC50 |
> 100 |
> 143 |
Inhibition of Yield |
||
NOEC |
100 |
143 |
LOEC |
> 100 |
> 143 |
EyC10 |
> 100 |
> 143 |
EyC20 |
> 100 |
> 143 |
EyC50 |
> 100 |
> 143 |
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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