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EC number: 218-747-8 | CAS number: 2224-33-1
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 1992
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- guideline study with acceptable restrictions
- Remarks:
- Test method according to OECD TG 301 C. No data on GLP.
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 C (Ready Biodegradability: Modified MITI Test (I))
- GLP compliance:
- not specified
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge (adaptation not specified)
- Details on inoculum:
- - Concentration of sludge: 30 mg/L
- Duration of test (contact time):
- 28 d
- Initial conc.:
- 100 mg/L
- Based on:
- test mat.
- Parameter followed for biodegradation estimation:
- TOC removal
- Key result
- Parameter:
- other: BOD (NO2)
- Value:
- 20
- Sampling time:
- 28 d
- Key result
- Parameter:
- other: BOD (NH3)
- Value:
- 26
- Sampling time:
- 28 d
- Key result
- Parameter:
- % degradation (TOC removal)
- Value:
- 28
- Sampling time:
- 28 d
- Validity criteria fulfilled:
- not specified
- Interpretation of results:
- under test conditions no biodegradation observed
- Conclusions:
- The test substance butan-2-one O,O',O''-(methylsilylidyne)trioxime was determined to be not readily biodegradable under test conditions.
- Executive summary:
The readily biodegradation test was performed by MITI according to OECD Guideline 301 C. 30 mg/L of activated sludge were exposed for 28 days to 100 mg/L of test item butan-2-one O,O',O''-(methylsilylidyne)trioxime. The biodegradation was analysed by indirect analysis, BOD (NO2) and BOD (NH3) obtaining a biodegradation of 20% and 26% respectively and by direct TOC analysis obtaining a biodegradation of 28%. The test substance was determined to be not readily biodegradable under test conditions.
The test substance was hydrolyzed to form 2-Butanone oxime (2-0546, persistence, Low-Bioconcentration), Monomethylsilanol, and polymer (Polysiloxane) of the Monomethylsilanol. Analysis of the test substance was difficult.
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- (Q)SAR
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- results derived from a valid (Q)SAR model and falling into its applicability domain, with adequate and reliable documentation / justification
- Remarks:
- Internationally accepted method, EPI-Suite, EPA (USA)
- Justification for type of information:
- See attached the QMRF and QPRF for the QSAR model.
- Principles of method if other than guideline:
- Calculation by EPI-Suite, EPA (USA) / BIOWIN v4.10
- GLP compliance:
- no
- Validity criteria fulfilled:
- not applicable
- Interpretation of results:
- under test conditions no biodegradation observed
- Conclusions:
- The substances butan-2-one O,O',O''-(vinylsilanetriyl)oxime is predicted not to be readily biodegradable by EPI-Suite, EPA (USA) / BIOWIN v4.10 calculation method.
- Executive summary:
The substances butan-2-one O,O',O''-(vinylsilanetriyl)oxime is predicted not to be readily biodegradable by EPI-Suite, EPA (USA) / BIOWIN v4.10 calculation method.
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- read-across from supporting substance (structural analogue or surrogate)
- Adequacy of study:
- key study
- Justification for type of information:
- REPORTING FORMAT FOR THE ANALOGUE APPROACH
The analogue Butan-2-one O,O',O''-(methylsilanetriyl)oxime which shares the same functional group with Butan-2-one O,O',O''-(vinylsilanetriyl)oxime, also has comparable values for the relevant molecular properties for biodegradation.
See attached the reporting format. - Reason / purpose for cross-reference:
- read-across source
- Key result
- Parameter:
- other: BOD (NO2)
- Value:
- 20
- Sampling time:
- 28 d
- Remarks on result:
- other: (Results based on analogue substance butan-2-one O,O',O''-(methylsilanetriyl)oxime)
- Key result
- Parameter:
- other: (NH3)
- Value:
- 26
- Sampling time:
- 28 d
- Remarks on result:
- other: (Results based on analogue substance butan-2-one O,O',O''-(methylsilanetriyl)oxime)
- Key result
- Parameter:
- % degradation (TOC removal)
- Value:
- 28
- Sampling time:
- 28 d
- Remarks on result:
- other: (Results based on analogue substance butan-2-one O,O',O''-(methylsilanetriyl)oxime)
- Details on results:
- The analogue substance butan-2-one O,O',O''-(methylsilanetriyl)oxime was hydrolyzed to form 2-Butanone oxime(2-0546, persistence, Low-Bioconcentration), Monomethylsilanol, and polymer (Polysiloxane) of the Monomethylsilanol. Analysis of the test substance was difficult. Based on these results the test item butan-2-one O,O',O''-(vinylsilanetriyl)oxime is also expected to hydrolyse to form 2-butanoe oxime and the corresponding silanol and polysiloxane.
- Validity criteria fulfilled:
- not specified
- Interpretation of results:
- under test conditions no biodegradation observed
- Conclusions:
- Based on the read-across approach from experimental results on analogue substance butan-2-one O,O',O''-(methylsilylidyne)trioxime, the test item butan-2-one O,O',O''-(vinylsilylidyne)trioxime was determined to be not readily biodegradable.
- Executive summary:
The readily biodegradation test was performed by MITI according to OECD Guideline 301 C on analogue substance butan-2-one O,O',O''-(methylsilylidyne)trioxime. 30 mg/L of activated sludge were exposed for 28 days to 100 mg/L. The biodegradation was analysed by indirect analysis, BOD (NO2) and BOD (NH3) obtaining a biodegradation of 20% and 26% respectively and by direct TOC analysis obtaining a biodegradation of 28%. Based on these results, the read-across was applied and the test item butan-2-one O,O',O''-(vinylsilylidyne)trioxime was determined to be not readily biodegradable under test conditions.
Referenceopen allclose all
The test substance was hydrolyzed to form 2-Butanone oxime(2-0546, persistence, Low-Bioconcentration), Monomethylsilanol, and polymer (Polysiloxane) of the Monomethylsilanol. Analysis of the test substance was difficult.
Degradation % results were:
Indirect analysis |
BOD (NO2) |
BOD (NH3) |
28, 9, 24 |
36, 12, 31 |
Direct analysis |
TOC |
34, 20, 31 |
The substances butan-2-one O,O',O''-(vinylsilanetriyl)oxime is predicted not to be readily biodegradable by EPI-Suite, EPA (USA) / BIOWIN v4.10.
Description of key information
Key study: Based on the read-across approach from experimental results (test method OECD 301C) on the analogue substance butan-2-one O,O',O''-(methylsilylidyne)trioxime, butan-2-one O,O',O''-(vinylsilylidyne)trioxime was determined to be not readily biodegradable.
Supporting study: EPI-Suite v4.1 (BIOWIN): Butan-2-one O,O',O''-(vinylsilanetriyl)oxime was predicted to not readily biodegradable.
Key value for chemical safety assessment
- Biodegradation in water:
- under test conditions no biodegradation observed
Additional information
Key study: Read-across from experimental data on analogue butan-2-one O,O',O''-(methylsilanetriyl)oxime:
A readily biodegradation test was performed by MITI according to OECD Guideline 301 C on analogue substance butan-2-one O,O',O''-(methylsilylidyne)trioxime. 30 mg/L of activated sludge were exposed for 28 days to 100 mg/L. The biodegradation was analysed by indirect analysis, BOD (NO2) and BOD (NH3) obtaining a biodegradation of 20% and 26% respectively and by direct TOC analysis obtaining a biodegradation of 28%. Based on these results, the read-across was applied and the test item butan-2-one O,O',O''-(vinylsilylidyne)trioxime was determined to be not readily biodegradable under test conditions.
Supporting study: According the the calculation method EPI-Suite, EPA (USA) / BIOWIN v4.10, butan-2-one O,O',O''-(vinylsilanetriyl)oxime was predicted to not readily biodegradable.
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