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EC number: 425-220-8 | CAS number: 5945-33-5
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Bioaccumulation: aquatic / sediment
Administrative data
Link to relevant study record(s)
Description of key information
BCF is 5
Key value for chemical safety assessment
- BCF (aquatic species):
- 5 dimensionless
Additional information
BCF was determined via a Bioconcentration Test (Semi-Static System) to Zebra-fish (Brachydanio rerio) in accordance with OECD Test Guideline 305.The study was conducted under semi-static conditions with the nominal concentration of 0.4 mg/L and solvent control for a period of 33 days. 250 test fish were used for each treatment and equally divided into 10 test containers. The test solution was renewed once every two days. During the exposure time, the mortality, number of abnormal fish and abnormal behavior of fish was observed and recorded once a day. The water sample and fish sample were taken to analyze the concentration of the test substance (BDP). The bioconcentration factor (BCF) value was calculated as the ratio (as BCFss) of concentration in the fish (Cf) and in the water (Cw) at the apparent steady-state. BDP was stable under test condition.During the test, based on the nominal concentration of 0.4 mg/L, the mean measured concentration of BDP test solution was 0.37 mg/Land standard deviation was 0.04.The steady state bioconcentration factor(BCFss)was determined to be 5, which therefore showed BDP is not bioaccumulative in Zebra fish (Brachydanio rerio).
The two models based on different mechanisms. One is a linnear model and the other is B-profile model. Both of them showed that the BCF of BDP is lower than 250 indicating the hazard potential caused by bioconcentration is low. Therefore BDP is not a bioaccumulative substance.Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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