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Toxicological information

Additional toxicological data

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Administrative data

Endpoint:
additional toxicological information
Type of information:
experimental study
Adequacy of study:
other information
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Acceptable, well documented publication which meets basic scientific principles.

Data source

Reference
Reference Type:
publication
Title:
A real-time fluorescence assay for measuring N-dealkylation
Author:
Mayer, R.T. et al.
Year:
2007
Bibliographic source:
Drugs Metabolism and Distribution, 35(1): 103 - 109

Materials and methods

Type of study / information:
N-Dealkylation of secondary amines

Results and discussion

Applicant's summary and conclusion