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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
activated sludge respiration inhibition testing
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: GLP study according EU/OECD guideline

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2004

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 209 (Activated Sludge, Respiration Inhibition Test
GLP compliance:
yes (incl. QA statement)

Test material

Constituent 1
Chemical structure
Reference substance name:
2,2-dimethylbutyric acid
EC Number:
209-865-0
EC Name:
2,2-dimethylbutyric acid
Cas Number:
595-37-9
Molecular formula:
C6H12O2
IUPAC Name:
2,2-dimethylbutanoic acid
Constituent 2
Reference substance name:
2,2-dimethyl butanoic acid
IUPAC Name:
2,2-dimethyl butanoic acid

Sampling and analysis

Analytical monitoring:
no

Test solutions

Vehicle:
no

Test organisms

Test organisms (species):
activated sludge

Study design

Test type:
static
Water media type:
freshwater
Limit test:
no
Total exposure duration:
3 h

Results and discussion

Effect concentrations
Duration:
3 h
Dose descriptor:
EC50
Effect conc.:
6 810 mg/L
Nominal / measured:
nominal
Basis for effect:
inhibition of total respiration
Remarks:
respiration rate

Any other information on results incl. tables

The test substance showed 51.4 % respiration inhibition of activated sludge at a test item concentration of 10000 mg/1.

The EC50 is 6810 mg/l.

Applicant's summary and conclusion

Validity criteria fulfilled:
yes