Registration Dossier

Administrative data

Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2008
Reliability:
1 (reliable without restriction)

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2008
Report Date:
2008

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
OECD Guideline 107 (Partition Coefficient (n-octanol / water), Shake Flask Method)
Deviations:
not specified
GLP compliance:
no
Type of method:
shake-flask method to: flask method
Partition coefficient type:
octanol-water

Test material

Reference
Name:
Unnamed
Type:
Constituent
Details on test material:
Purity: 98.01 % without water

Study design

Analytical method:
high-performance liquid chromatography

Results and discussion

Partition coefficient
Type:
log Pow
Partition coefficient:
1.45
Temp.:
23 °C
pH:
ca. 7
Details on results:
determ. no. stock solution water test substance conc. test substance conc. log Pow
[ml] [ml] in n-octanol phase [mg/l] in water phase [mg/l]
A1 5 10 13.1 0.33 1.59
A2 5 10 13.5 0.35 1.58
B1 10 10 13.6 0.46 1.47
B2 10 10 13.5 0.46 1.47
C1 20 10 13.3 0.66 1.31
C2 20 10 13.4 0.69 1.29
mean 1.45

Applicant's summary and conclusion

Conclusions:
The Log Pow of the test item, determined according OECD 107 (shake flask method ) is 1.45 at 23°C