Registration Dossier
Registration Dossier
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EC number: 256-435-3 | CAS number: 49701-24-8
Stability in organic solvents and identity of relevant degradation products
Administrative data
- Endpoint:
- stability in organic solvents and identity of relevant degradation products
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Study period:
- 2013
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: well performed estimation
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 013
- Report date:
- 2013
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: company SOP
- Principles of method if other than guideline:
- Stirring a solution of the substance in the corresponding solvent for 72 hours at room temperature and comparison of the HPLC plots with the original solution.
- GLP compliance:
- no
Test material
- Reference substance name:
- 4-amino-2,5-dimethoxy-N-methylbenzenesulphonamide
- EC Number:
- 256-435-3
- EC Name:
- 4-amino-2,5-dimethoxy-N-methylbenzenesulphonamide
- Cas Number:
- 49701-24-8
- Molecular formula:
- C9H14N2O4S
- IUPAC Name:
- 4-amino-2,5-dimethoxy-N-methylbenzene-1-sulfonamide
- Details on test material:
- Purity: 99.7%
Constituent 1
Results and discussion
- Test substance stable:
- yes
- Transformation products:
- not measured
Applicant's summary and conclusion
- Conclusions:
- The test substance is stable and homogeneous for more than 72 hours in DMSO (0.1 and 50 mg/ml) and in ethanol (0.1 mg/ml) at room temperature. The solubility of the test substance in ethanol is not high enough for testing stability at 50 mg/ml.
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